Skp2 inhibitor C1 (SKPin C1) - Names and Identifiers
Skp2 inhibitor C1 (SKPin C1) - Physico-chemical Properties
Molecular Formula | C18H13BrN2O4S2
|
Molar Mass | 465.34 |
Density | 1.74±0.1 g/cm3(Predicted) |
Boling Point | 655.3±65.0 °C(Predicted) |
Solubility | DMSO: 6.4 mg/mL (Need ultrasonic) |
pKa | 2.97±0.10(Predicted) |
Storage Condition | -20℃ |
In vitro study | Treatment of MCF-7 cells with Skp2 inhibitor C1 reduced the proportion of cells in the G1 phase and increased the number of cells in the G2/M phase. |
Skp2 inhibitor C1 (SKPin C1) - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.149 ml | 10.745 ml | 21.49 ml |
5 mM | 0.43 ml | 2.149 ml | 4.298 ml |
10 mM | 0.215 ml | 1.074 ml | 2.149 ml |
5 mM | 0.043 ml | 0.215 ml | 0.43 ml |
Last Update:2024-01-02 23:10:35
Skp2 inhibitor C1 (SKPin C1) - Reference Information
biological activity | Skp2 inhibitor C1 (SKPin C1) is a highly selective small molecule inhibitor of Skp2-mediated p27 degradation. |
target | TargetValue p27 degradation () |
Target | Value |
in vitro study | treating MCF-7 cells with Skp2 inhibitor C1 can reduce the proportion of G1 phase cells and increase the number of G2/M phase cells. |
Last Update:2024-04-09 21:04:16